Adenosine A2b Receptor Antikörper (AA 145-328)

Produktnummer ABIN7600066

Dieser Anti-Adenosine A2b Receptor Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Adenosine A2b Receptor in WB, ELISA, IF, FACS und ICC. Geeignet für Human.

Kurzübersicht für Adenosine A2b Receptor Antikörper (AA 145-328) (ABIN7600066)

Target: Adenosine A2b Receptor (ADORA2B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A2b Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-Adenosine A2b Receptor Antikörper

Bindungsspezifität: AA 145-328

Verwendungszweck: Anti-ADORA2B Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-ADORA2B Antibody Picoband® (ABIN7600066). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ADORA2B recombinant protein (Position: N145-L328).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Corset, V., Nguyen-Ba-Charvet, K. T., Forcet, C., Moyse, E., Chedotal, A., Mehlen, P. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor. Nature 407: 747-750, 2000. 2. Kataoka, S., Baquero, A., Yang, D., Shultz, N., Vandenbeuch, A., Ravid, K., Kinnamon, S. C., Finger, T. E. A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. PLoS One 7: e30032, 2012. Note: Electronic Article. 3. Libert, F., Passage, E., Parmentier, M., Simons, M.-J., Vassart, G., Mattei, M.-G. Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor. Genomics 11: 225-227, 1991. Note: Erratum: Genomics 23: 305 only, 1994.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Andere Bezeichnung: ADORA2B

Hintergrund:

Synonyms: Zinc finger protein Helios, Ikaros family zinc finger protein 2, IKZF2, HELIOS, ZNFN1A2

Tissue Specificity: Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Background: The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which encodes it. This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.

Molekulargewicht: 41 kDa

Gen-ID: 136

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process